Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation

Pure tense (T) and relaxed (R) quaternary state polymerized human hemoglobins (PolyhHbs) were synthesized and their biophysical properties characterized, along with mixtures of T- and R-state PolyhHbs. It was observed that the oxygen affinity of PolyhHb mixtures varied linearly with T-state mole fra...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Belcher, Donald Andrew, Banerjee, Uddyalok, Baehr, Christopher Michael, Richardson, Kristopher Emil, Cabrales, Pedro, Berthiaume, François, Palmer, Andre Francis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636107/
https://ncbi.nlm.nih.gov/pubmed/29020036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185988
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