Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation

Pure tense (T) and relaxed (R) quaternary state polymerized human hemoglobins (PolyhHbs) were synthesized and their biophysical properties characterized, along with mixtures of T- and R-state PolyhHbs. It was observed that the oxygen affinity of PolyhHb mixtures varied linearly with T-state mole fra...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Belcher, Donald Andrew, Banerjee, Uddyalok, Baehr, Christopher Michael, Richardson, Kristopher Emil, Cabrales, Pedro, Berthiaume, François, Palmer, Andre Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636107/
https://ncbi.nlm.nih.gov/pubmed/29020036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185988
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