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Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1)

X chromosome inactivation is an epigenetic dosage compensation mechanism in female mammals driven by the long noncoding RNA, Xist. Although recent genomic and proteomic approaches have provided a more global view of Xist’s function, how Xist RNA localizes to the inactive X chromosome (Xi) and spread...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sunwoo, Hongjae, Colognori, David, Froberg, John E., Jeon, Yesu, Lee, Jeannie T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635913/
https://ncbi.nlm.nih.gov/pubmed/28923964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711206114
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