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Xist Repeats A and B account for two distinct phases of X-inactivation establishment
Colognori, Sunwoo et al. show that X-inactivation establishment is a biphasic process with distinct genetic requirements. Repeat A initiates Polycomb recruitment and gene silencing, whereas Repeat B stabilizes them. Surprisingly, X-inactivation can initiate without Repeat B. Without Repeat A, howeve...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362899/ https://ncbi.nlm.nih.gov/pubmed/32531209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.05.021 |
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