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Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen

Successful pathogens use complex signaling mechanisms to monitor their environment and reprogram global gene expression during specific stages of infection. Group A Streptococcus (GAS) is a major human pathogen that causes significant disease burden worldwide. A secreted cysteine protease known as s...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Do, Hackwon, Makthal, Nishanth, VanderWal, Arica R., Rettel, Mandy, Savitski, Mikhail M., Peschek, Nikolai, Papenfort, Kai, Olsen, Randall J., Musser, James M., Kumaraswami, Muthiah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635878/
https://ncbi.nlm.nih.gov/pubmed/28923955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705972114
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