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Diverse p53/DNA binding modes expand the repertoire of p53 response elements
The tumor suppressor protein p53 acts as a transcription factor, binding sequence-specifically to defined DNA sites, thereby activating the expression of genes leading to diverse cellular outcomes. Canonical p53 response elements (REs) are made of two decameric half-sites separated by a variable num...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635862/ https://ncbi.nlm.nih.gov/pubmed/28912355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618005114 |
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