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Low-level p53 expression changes transactivation rules and reveals superactivating sequences

Transcriptional activation by the tumor suppressor p53 is considered to depend on cellular level, although there are few systems where this dependence on cellular level of p53 has been directly addressed. Previously, we reported that transactivation from p53 targets was sensitive to both p53 amount...

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Detalhes bibliográficos
Main Authors: Jordan, Jennifer J., Menendez, Daniel, Sharav, Jenia, Beno, Itai, Rosenthal, Karin, Resnick, Michael A., Haran, Tali E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437869/
https://ncbi.nlm.nih.gov/pubmed/22908277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205971109
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