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The complex architecture of p53 binding sites

Sequence-specific protein-DNA interactions are at the heart of the response of the tumor-suppressor p53 to numerous physiological and stress-related signals. Large variability has been previously reported in p53 binding to and transactivating from p53 response elements (REs) due, at least in part, t...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Senitzki, Alon, Safieh, Jessy, Sharma, Vasundhara, Golovenko, Dmitrij, Danin-Poleg, Yael, Inga, Alberto, Haran, Tali E
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897521/
https://ncbi.nlm.nih.gov/pubmed/33444431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1283
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