POLYCOMB RESPONDS TO LOW LEVELS OF TRANSCRIPTION

How is Polycomb (Pc), a eukaryotic negative regulator of transcription, targeted to specific mammalian genes? Our genome-wide analysis of the Pc mark H3K27me3 in murine cells that revealed Pc is preferentially associated with CpG island promoters of genes that are transcribed at a low level, and les...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Berrozpe, Georgina, Bryant, Gene O., Warpinski, Katherine, Spagna, Dan, Narayan, Santosh, Shah, Shivangi, Ptashne, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635825/
https://ncbi.nlm.nih.gov/pubmed/28746865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.076
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