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An effect of DNA sequence on nucleosome occupancy and removal

A barrier phases nucleosomes at the yeast (S. cerevisiae) GAL1/10 genes. Here we separate nucleosome positioning from occupancy, and show that the degree of occupancy of these phased sites is predictably determined by the underlying DNA sequences. As this occupancy is increased (by sequence alterati...

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Autori principali: Wang, Xin, Bryant, Gene O., Floer, Monique, Spagna, Dan, Ptashne, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071895/
https://ncbi.nlm.nih.gov/pubmed/21378966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2017
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