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A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding
How is chromatin architecture established and what role does it play in activation of transcription? We show that a regulatory locus in yeast (the UASg) bears, in addition to binding sites for the activator Gal4, sites bound by the protein RSC. RSC tightly positions a nucleosome, evidently partially...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032599/ https://ncbi.nlm.nih.gov/pubmed/20434983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.048 |
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