A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding

How is chromatin architecture established and what role does it play in activation of transcription? We show that a regulatory locus in yeast (the UASg) bears, in addition to binding sites for the activator Gal4, sites bound by the protein RSC. RSC tightly positions a nucleosome, evidently partially...

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Bibliografiske detaljer
Main Authors:	Floer, Monique, Wang, Xin, Prabhu, Vidya, Berrozpe, Georgina, Narayan, Santosh, Spagna, Dan, Alvarez, David, Kendall, Jude, Krasnitz, Alexander, Stepansky, Asya, Hicks, James, Bryant, Gene O., Ptashne, Mark
Format:	Artigo
Sprog:	Inglês
Udgivet:	2010
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3032599/ https://ncbi.nlm.nih.gov/pubmed/20434983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.048
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A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding

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