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Deletion of transcription factor binding motifs using the CRISPR/spCas9 system in the β-globin LCR

Transcription factors play roles in gene transcription through direct binding to their motifs in genome, and inhibiting this binding provides an effective strategy for studying their roles. Here, we applied the CRISPR (clustered, regularly interspaced, short palindromic repeat)/spCas9 (CRISPR-associ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biosci Rep
Egile Nagusiak: Kim, Yea Woon, Kim, AeRi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634328/
https://ncbi.nlm.nih.gov/pubmed/28729249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170976
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