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Deletion of transcription factor binding motifs using the CRISPR/spCas9 system in the β-globin LCR
Transcription factors play roles in gene transcription through direct binding to their motifs in genome, and inhibiting this binding provides an effective strategy for studying their roles. Here, we applied the CRISPR (clustered, regularly interspaced, short palindromic repeat)/spCas9 (CRISPR-associ...
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| Publicado no: | Biosci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5634328/ https://ncbi.nlm.nih.gov/pubmed/28729249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170976 |
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