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Enantioselective Nazarov cyclization of indole enones cooperatively catalyzed by Lewis acids and chiral Brønsted acids

Enantioselective control of the chirality of a tertiary α-carbon in the products of a Nazarov cyclization of enones is challenging because the reaction involves an enantioselective proton transfer process. We herein report the use of cooperative catalysis using Lewis acids and chiral Brønsted acids...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wang, Guo-Peng, Chen, Meng-Qing, Zhu, Shou-Fei, Zhou, Qi-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633839/
https://ncbi.nlm.nih.gov/pubmed/29081952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03183a
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