IL-12p35 Inhibits Neuroinflammation and Ameliorates Autoimmune Encephalomyelitis

Multiple sclerosis (MS) is an inflammatory demyelinating disease in which cytokines produced by immune cells that infiltrate the brain and spinal cord play a central role. We show here that the IL-12p35, the alpha subunit of IL-12 or IL-35 cytokine, might be an effective biologic for suppressing neu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Choi, Jin Kyeong, Dambuza, Ivy M., He, Chang, Yu, Cheng-Rong, Uche, Anita N., Mattapallil, Mary J., Caspi, Rachel R., Egwuagu, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633738/
https://ncbi.nlm.nih.gov/pubmed/29051763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01258
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