A carregar...
Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities
Antithrombin mainly inhibits factor Xa and thrombin. The reactive center loop (RCL) is crucial for its interactions with its protease targets and is fully inserted into the A-sheet after its cleavage, causing translocation of the covalently linked protease to the opposite end of the A-sheet. Antithr...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5633112/ https://ncbi.nlm.nih.gov/pubmed/28743742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787325 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|