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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

The present review is a sequel to the previous review on cancer metabolism published in this journal. This review focuses on the selective antiproliferative and cytotoxic effects of mitochondria-targeted therapeutics (MTTs) in cancer cells. Emerging research reveals a key role of mitochondrial respi...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Lopez, Marcos, Joseph, Joy, Zielonka, Jacek, Dwinell, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633086/
https://ncbi.nlm.nih.gov/pubmed/29017115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.09.020
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