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Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess
Tetrahydrobiopterin (BH(4)) is a common coenzyme of phenylalanine-, tyrosine-, and tryptophan hydroxylases, alkylglycerol monooxygenase, and NO synthases (NOS). Synthetic BH(4) is used medicinally for BH(4)-responsive phenylketonuria and inherited BH(4) deficiency. BH(4) supplementation has also dra...
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| Publicado no: | Mol Cell Biochem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632347/ https://ncbi.nlm.nih.gov/pubmed/28534121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-3060-7 |
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