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Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3

Human OAT1 and OAT3 play major roles in renal drug elimination and drug-drug interactions. However, there is little information on the interactions of drug metabolites with transporters. The goal of this study was to characterize the interactions of drug metabolites with OAT1 and OAT3 and compare th...

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Dettagli Bibliografici
Pubblicato in:J Pharm Sci
Autori principali: Zou, Ling, Matsson€, Par, Stecula, Adrian, Ngo, Huy X., Zur, Arik A., Giacomini, Kathleen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177813/
https://ncbi.nlm.nih.gov/pubmed/32910949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.09.004
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