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Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3)
This study examined the selectivity of organic anion transporters OAT1 and OAT3 for structural congeners of the heavy metal chelator 2,3-dimercapto-1-propanesulfonic acid (DMPS). Thiol-reactive reagents were also used to test structural predictions based on a homology model of OAT1 structure. DMPS w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154592/ https://ncbi.nlm.nih.gov/pubmed/21543413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00735.2010 |
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