Delayed Dosing of S-033188, a Novel Inhibitor of Influenza Virus Cap-dependent Endonuclease, Exhibited Significant Reduction of Viral Titer and Mortality in Mice Infected with Influenza A Virus

BACKGROUND: Both epidemic and pandemic influenza are major public health concerns, but current standard treatment limits its usage by 48 hours from onsets. Furthermore, no antiviral drug has been shown to definitively reduce serious complications, hospitalization, or mortality in a randomized clinic...

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Detaylı Bibliyografya
Yayımlandı:Open Forum Infect Dis
Asıl Yazarlar: Fukao, Keita, Ando, Yoshinori, Noshi, Takeshi, Kawai, Makoto, Yoshida, Ryu, Shishido, Takao, Naito, Akira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
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Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631482/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1210
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