Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers

AIM: The aim of this study was to generate and characterize scFv antibodies directed to human CD44v6, as well as to radiolabel and evaluate top candidates in vitro and in vivo for their potential use in CD44v6-targeted molecular imaging in cancer patients. MATERIALS AND METHODS: Phage display select...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Haylock, Anna-Karin, Nilvebrant, Johan, Mortensen, Anja, Velikyan, Irina, Nestor, Marika, Falk, Ronny
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630320/
https://ncbi.nlm.nih.gov/pubmed/29029420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17996
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