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Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

We have developed the CD44v6-targeting human bivalent antibody fragment AbD19384, an engineered recombinant human bivalent Fab antibody formed via dimerization of dHLX (synthetic double helix loop helix motif) domains, for potential use in antibody-based molecular imaging of squamous cell carcinoma...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: HAYLOCK, ANNA-KARIN, SPIEGELBERG, DIANA, MORTENSEN, ANJA C., SELVARAJU, RAM K., NILVEBRANT, JOHAN, ERIKSSON, OLOF, TOLMACHEV, VLADIMIR, NESTOR, MARIKA V.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725455/
https://ncbi.nlm.nih.gov/pubmed/26676731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3290
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