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Targeting TGF-β Signaling for Therapeutic Gain
Transforming growth factor βs (TGF-βs) are closely related ligands that have pleiotropic activity on most cell types of the body. They act through common heterotetrameric TGF-β type II and type I transmembrane dual specificity kinase receptor complexes, and the outcome of signaling is context-depend...
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| Publicado en: | Cold Spring Harb Perspect Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5630004/ https://ncbi.nlm.nih.gov/pubmed/28246179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a022301 |
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