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EGFR/TGFα and TGFβ/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets
Neuroendocrine neoplasms (NENs) are a heterogeneous family of malignancies whose proliferation is partially dependent on growth factors secreted by the microenvironment and the tumor itself. Growth factors of demonstrated importance in experimental models of NENs include EGF, TGFα, TGFβ and CTGF. EG...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684083/ https://ncbi.nlm.nih.gov/pubmed/22710195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334891 |
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