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EGFR/TGFα and TGFβ/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets

Neuroendocrine neoplasms (NENs) are a heterogeneous family of malignancies whose proliferation is partially dependent on growth factors secreted by the microenvironment and the tumor itself. Growth factors of demonstrated importance in experimental models of NENs include EGF, TGFα, TGFβ and CTGF. EG...

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Bibliografski detalji
Glavni autori: Kidd, M., Schimmack, S., Lawrence, B., Alaimo, D., Modlin, I.M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684083/
https://ncbi.nlm.nih.gov/pubmed/22710195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334891
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