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Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells

Ikaros is a transcription factor that regulates lymphocyte development from the level of the haematopoietic stem cell. Lack of Ikaros reduces the ability of progenitor cells to commit to the T‐cell lineage, resulting in reduced numbers of early thymic T‐cell progenitors and mature T cells. Mature CD...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Immunology
मुख्य लेखकों: Agnihotri, Parul, Robertson, Nicholas M., Umetsu, Sarah E., Arakcheeva, Ksenia, Winandy, Susan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629446/
https://ncbi.nlm.nih.gov/pubmed/28670688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12786
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