Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells

Ikaros is a transcription factor that regulates lymphocyte development from the level of the haematopoietic stem cell. Lack of Ikaros reduces the ability of progenitor cells to commit to the T‐cell lineage, resulting in reduced numbers of early thymic T‐cell progenitors and mature T cells. Mature CD...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Immunology
Huvudupphovsmän: Agnihotri, Parul, Robertson, Nicholas M., Umetsu, Sarah E., Arakcheeva, Ksenia, Winandy, Susan
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629446/
https://ncbi.nlm.nih.gov/pubmed/28670688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12786
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk