Φορτώνει......
Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells
Ikaros is a transcription factor that regulates lymphocyte development from the level of the haematopoietic stem cell. Lack of Ikaros reduces the ability of progenitor cells to commit to the T‐cell lineage, resulting in reduced numbers of early thymic T‐cell progenitors and mature T cells. Mature CD...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Immunology |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629446/ https://ncbi.nlm.nih.gov/pubmed/28670688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12786 |
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