טוען...
Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells
Ikaros is a transcription factor that regulates lymphocyte development from the level of the haematopoietic stem cell. Lack of Ikaros reduces the ability of progenitor cells to commit to the T‐cell lineage, resulting in reduced numbers of early thymic T‐cell progenitors and mature T cells. Mature CD...
שמור ב:
הוצא לאור ב: | Immunology |
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Main Authors: | , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
John Wiley and Sons Inc.
2017
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629446/ https://ncbi.nlm.nih.gov/pubmed/28670688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12786 |
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