Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes

Protein cysteinyl residues are the mediators of hydrogen peroxide (H(2)O(2))-dependent redox signaling. However, site-specific mapping of the selectivity and dynamics of these redox reactions in cells poses a major analytical challenge. Here we describe a chemoproteomic platform to systematically an...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Fu, Ling, Liu, Keke, Sun, Mingan, Tian, Caiping, Sun, Rui, Morales Betanzos, Carlos, Tallman, Keri A., Porter, Ned A., Yang, Yong, Guo, Dianjing, Liebler, Daniel C., Yang, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629266/
https://ncbi.nlm.nih.gov/pubmed/28827280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000108
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