Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Contractile adherens junctions support cell−cell adhesion, epithelial integrity, and morphogenesis. Much effort has been devoted to understanding how contractility is established; however, less is known about whether contractility can be actively downregulated at junctions nor what function this mig...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Liang, Xuan, Budnar, Srikanth, Gupta, Shafali, Verma, Suzie, Han, Siew-Ping, Hill, Michelle M., Daly, Roger J., Parton, Robert G., Hamilton, Nicholas A., Gomez, Guillermo A., Yap, Alpha S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629210/
https://ncbi.nlm.nih.gov/pubmed/28983097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00797-w
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