Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens

Cadherin junctions arise from the integrated action of cell adhesion, signaling, and the cytoskeleton. At the zonula adherens (ZA), a WAVE2-Arp2/3 actin nucleation apparatus is necessary for junctional tension and integrity. But how this is coordinated with cadherin adhesion is not known. We now ide...

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Main Authors: Han, Siew Ping, Gambin, Yann, Gomez, Guillermo A., Verma, Suzie, Giles, Nichole, Michael, Magdalene, Wu, Selwin K., Guo, Zhong, Johnston, Wayne, Sierecki, Emma, Parton, Robert G., Alexandrov, Kirill, Yap, Alpha S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953287/
https://ncbi.nlm.nih.gov/pubmed/24469447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544478
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