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Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

The biological impact of Rho depends critically on the precise subcellular localization of its active, GTP-loaded form. The spatio-temporal balance between molecules that promote nucleotide exchange or GTP hydrolysis can potentially determine the sites of Rho signalling. But how these activities may...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ratheesh, Aparna, Gomez, Guillermo A., Priya, Rashmi, Verma, Suzie, Kovacs, Eva M., Jiang, Kai, Brown, Nicholas H., Akhmanova, Anna, Stehbens, Samantha J., Yap, Alpha S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939354/
https://ncbi.nlm.nih.gov/pubmed/22750944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2532
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