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p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis

The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian sperm...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Napoletano, Francesco, Gibert, Benjamin, Yacobi-Sharon, Keren, Vincent, Stéphane, Favrot, Clémentine, Mehlen, Patrick, Girard, Victor, Teil, Margaux, Chatelain, Gilles, Walter, Ludivine, Arama, Eli, Mollereau, Bertrand
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629030/
https://ncbi.nlm.nih.gov/pubmed/28945745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007024
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