p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis

The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian sperm...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Napoletano, Francesco, Gibert, Benjamin, Yacobi-Sharon, Keren, Vincent, Stéphane, Favrot, Clémentine, Mehlen, Patrick, Girard, Victor, Teil, Margaux, Chatelain, Gilles, Walter, Ludivine, Arama, Eli, Mollereau, Bertrand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629030/
https://ncbi.nlm.nih.gov/pubmed/28945745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007024
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