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p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.

The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian sperm...

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Detalhes bibliográficos
Main Authors: Francesco Napoletano, Benjamin Gibert, Keren Yacobi-Sharon, Stéphane Vincent, Clémentine Favrot, Patrick Mehlen, Victor Girard, Margaux Teil, Gilles Chatelain, Ludivine Walter, Eli Arama, Bertrand Mollereau
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-09-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC5629030?pdf=render
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