DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

During Drosophila embryonic development, cell death eliminates 30% of the primordial germ cells (PGCs). Inhibiting apoptosis does not prevent PGC death, suggesting a divergence from the conventional apoptotic program. Here, we demonstrate that PGCs normally activate an intrinsic alternative cell dea...

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Publicado en:Nat Commun
Main Authors: Tarayrah-Ibraheim, Lama, Maurice, Elital Chass, Hadary, Guy, Ben-Hur, Sharon, Kolpakova, Alina, Braun, Tslil, Peleg, Yoav, Yacobi-Sharon, Keren, Arama, Eli
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052343/
https://ncbi.nlm.nih.gov/pubmed/33863891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22622-1
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