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Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges

The past decade has been proclaimed as a hugely successful era of gene discovery through the high yields of many genome-wide association studies (GWAS). However, much of the perceived benefit of such discoveries lies in the promise that the identification of genes that influence disease would direct...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Paternoster, Lavinia, Tilling, Kate, Davey Smith, George
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628782/
https://ncbi.nlm.nih.gov/pubmed/28981501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006944
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