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Methodological challenges in Mendelian randomization

We give critical attention to the assumptions underlying Mendelian randomization analysis and their biological plausibility. Several scenarios violating the Mendelian randomization assumptions are described, including settings with inadequate phenotype definition, the setting of time-varying exposur...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: VanderWeele, Tyler J., Tchetgen Tchetgen, Eric J., Cornelis, Marilyn, Kraft, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981897/
https://ncbi.nlm.nih.gov/pubmed/24681576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0000000000000081
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