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Methodological challenges in Mendelian randomization
We give critical attention to the assumptions underlying Mendelian randomization analysis and their biological plausibility. Several scenarios violating the Mendelian randomization assumptions are described, including settings with inadequate phenotype definition, the setting of time-varying exposur...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981897/ https://ncbi.nlm.nih.gov/pubmed/24681576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0000000000000081 |
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