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Precision spherical nucleic acids for delivery of anticancer drugs

We report a spherical nucleic acid (SNA) system for the delivery of BKM120, an anticancer drug for treatment of chronic lymphocytic leukemia (CLL). While promising for cancer treatment, this drug crosses the blood–brain barrier causing significant side-effects in patients. The DNA nanoparticle encap...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Bousmail, Danny, Amrein, Lilian, Fakhoury, Johans J., Fakih, Hassan H., Hsu, John C. C., Panasci, Lawrence, Sleiman, Hanadi F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628336/
https://ncbi.nlm.nih.gov/pubmed/28989655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01619k
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