Precision spherical nucleic acids for delivery of anticancer drugs

We report a spherical nucleic acid (SNA) system for the delivery of BKM120, an anticancer drug for treatment of chronic lymphocytic leukemia (CLL). While promising for cancer treatment, this drug crosses the blood–brain barrier causing significant side-effects in patients. The DNA nanoparticle encap...

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Bibliografski detalji
Izdano u:Chem Sci
Glavni autori: Bousmail, Danny, Amrein, Lilian, Fakhoury, Johans J., Fakih, Hassan H., Hsu, John C. C., Panasci, Lawrence, Sleiman, Hanadi F.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Chemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628336/
https://ncbi.nlm.nih.gov/pubmed/28989655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01619k
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