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Toxicological implications of mitochondrial localization of CYP2E1

Cytochrome P450 2E1 (CYP2E1) metabolizes an extensive array of pollutants, drugs, and other small molecules, often resulting in bioactivation to reactive metabolites. Therefore, it is unsurprising that it has been the subject of decades of research publications and reviews. However, while CYP2E1 has...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Hartman, Jessica H., Miller, Grover P., Meyer, Joel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627779/
https://ncbi.nlm.nih.gov/pubmed/28989700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00020k
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