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Subcellular Localization of Rat CYP2E1 Impacts Metabolic Efficiency toward Common Substrates
Cytochrome P450 2E1 (CYP2E1) detoxifies or bioactivates many low molecular-weight compounds. Most knowledge about CYP2E1 activity relies on studies of the enzyme localized to endoplasmic reticulum (erCYP2E1); however, CYP2E1 undergoes transport to mitochondria (mtCYP2E1) and becomes metabolically ac...
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| Publicado no: | Toxicology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658230/ https://ncbi.nlm.nih.gov/pubmed/26463279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2015.10.001 |
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