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Cooperative effects for CYP2E1 differ between styrene and its metabolites
1. Cooperative interactions are frequently observed in the metabolism of drugs and pollutants by cytochrome P450s; nevertheless, the molecular determinants for cooperativity remain elusive. Previously, we demonstrated that steady-state styrene metabolism by CYP2E1 exhibits positive cooperativity. 2....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979932/ https://ncbi.nlm.nih.gov/pubmed/23327532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2012.760764 |
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