Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide adenine dinucleotide (NAD) levels are crucial for liver function. The saturated fatty acid palmitate and the unsaturated fatty acid oleate are the main free fatty acids in adipose tissue and human diet. We asked how these fa...

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Bibliografische gegevens
Gepubliceerd in:Lipids Health Dis
Hoofdauteurs: Penke, Melanie, Schuster, Susanne, Gorski, Theresa, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627432/
https://ncbi.nlm.nih.gov/pubmed/28974242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0583-6
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