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Tuning SpyTag–SpyCatcher mutant pairs toward orthogonal reactivity encryption
Genetically encoded covalent peptide tagging technology, such as the SpyTag–SpyCatcher reaction, has emerged as a unique way to do chemistry with proteins. Herein, we report the reactivity engineering of SpyTag–SpyCatcher mutant pairs and show that distinct reactivity can be encrypted for the same r...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627348/ https://ncbi.nlm.nih.gov/pubmed/28989685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02686b |
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