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A machine-learning heuristic to improve gene score prediction of polygenic traits
Machine-learning techniques have helped solve a broad range of prediction problems, yet are not widely used to build polygenic risk scores for the prediction of complex traits. We propose a novel heuristic based on machine-learning techniques (GraBLD) to boost the predictive performance of polygenic...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627249/ https://ncbi.nlm.nih.gov/pubmed/28979001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13056-1 |
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