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Progress in understanding the molecular mechanism of Xist RNA function through genetics

The Xist gene produces a long noncoding RNA that initiates chromosome-wide gene repression on the inactive X chromosome in female mammals. Recent progress has advanced the understanding of Xist function at the molecular level. This review provides an overview of insights from genetic approaches and...

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Bibliographic Details
Published in:Philos Trans R Soc Lond B Biol Sci
Main Authors: Monfort, Asun, Wutz, Anton
Format: Artigo
Language:Inglês
Published: The Royal Society 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627166/
https://ncbi.nlm.nih.gov/pubmed/28947663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0368
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