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Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-positive Prostate Cancer Cells

The oncogenic activation of the ETS related gene (ERG) due to gene fusions is present in over half of prostate cancer (CaP) in Western countries. Due to its high incidence and oncogenic role, ERG and components of ERG network have emerged as potential drug targets for CaP. Utilizing gene expression...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Mohamed, Ahmed A., Tan, Shyh-Han, Xavier, Charles P., Katta, Shilpa, Huang, Wei, Ravindranath, Lakshmi, Jamal, Muhammad, Li, Hua, Srivastava, Meera, Srivatsan, Eri, Sreenath, Taduru, McLeod, David G., Srinivasan, Alagarsamy, Petrovics, Gyorgy, Dobi, Albert, Srivastava, Shiv
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626592/
https://ncbi.nlm.nih.gov/pubmed/28607007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0058
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