Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-positive Prostate Cancer Cells

The oncogenic activation of the ETS related gene (ERG) due to gene fusions is present in over half of prostate cancer (CaP) in Western countries. Due to its high incidence and oncogenic role, ERG and components of ERG network have emerged as potential drug targets for CaP. Utilizing gene expression...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Mohamed, Ahmed A., Tan, Shyh-Han, Xavier, Charles P., Katta, Shilpa, Huang, Wei, Ravindranath, Lakshmi, Jamal, Muhammad, Li, Hua, Srivastava, Meera, Srivatsan, Eri, Sreenath, Taduru, McLeod, David G., Srinivasan, Alagarsamy, Petrovics, Gyorgy, Dobi, Albert, Srivastava, Shiv
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626592/
https://ncbi.nlm.nih.gov/pubmed/28607007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0058
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg